• Login
    View Item 
    •   DSpace Home
    • School of Medicine
    • Journal Papers in PubMed
    • View Item
    •   DSpace Home
    • School of Medicine
    • Journal Papers in PubMed
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Secondary repair of alveolar clefts using human mesenchymal stem cells.

    Thumbnail
    Date
    2009-Aug
    Author
    Hossein Behnia
    Arash Khojasteh
    Masoud Soleimani
    Azita Tehranchi
    Ahad Khoshzaban
    Saeed Hidari Keshel
    Reza Atashi
    Metadata
    Show full item record
    Abstract
    Recently tissue engineering has become available as a regenerative treatment for bone defects; however, little has been reported on the application of tissue engineering for regeneration of cleft defect tissues. Mesenchymal-derived stem cells were applied to different kinds of bone substitute and compared in different animal models, but their usage in human critical defects remained unclear. In this study we report 2 patients with unilateral alveolar cleft, treated with the composite scaffold of demineralized bone mineral and calcium sulphate (Osteoset) loaded with mesenchymal stem cells (MSCs). Computed tomograms showed 34.5% regenerated bone, extending from the cleft walls and bridging the cleft after 4 months in one case and in the other there was 25.6% presentation of bone integrity. The available data revealed the conventional bone substitute was not a suitable scaffold for the MSC-induced bone regeneration.
    DOI
    http://dx.doi.org/10.1016/j.tripleo.2009.03.040
    Collections
    • Journal Papers in PubMed

    Contact Us | Send Feedback
     

     

    Browse

    All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Contact Us | Send Feedback