The anti-mycobacterial activity of the extract of Ferula gummosa
M. Karimi Yazdi
P. Khiabani Rad
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© 2015. Objective: Over the last decades, great advances in the treatment and prevention of infectious diseases have fostered complacency about infection in a society which has access to antibiotics. However, infections and also adverse reactions of such drugs remain. Also, due to the increasing demand for less toxic and more potent antibiotics, it is necessary to find new sources. Galbanum has a fresh, earthy, balsamic, woody, spicy scent. It may be used in the aromatherapy treatment of abscesses, acne, boils, bronchitis, cuts, lice, mature skin, muscle aches, poor circulation, rheumatism, scars, sores, stretch marks, and wounds. Method: In this research, antimycobacterial activity of the extract of the root and fruit of Ferula gummosa was investigated and was tested against Mycobacterium bovis. The extract of the fruit was achieved by using the maceration method, and the effect of different concentrations of the extract on the growth of Mycobacterium was compared with the standard 1 MC Farland. The quantity of colonies was investigated by the microscopic method. Streptomycin was used for the control of anti-mycobacterial test systems. Result: The result showed that Galbanum of 0.03 and 0.04. g/ml have a protection effect, and the other concentrations of extract have a decreasing effect on the growth of M. bovis. Conclusion: Considering the side effects of antimycobacterial drugs, more research into some natural plants for the treatment of mycobacterial disease is necessary. In this in vitro study, the effect of Galbanum against M. bovis is highlighted.Antibacterial activity of the essential oil from the F. gummosa seed: Eftekhar et al.; Antibacterial activity of F. gummosa essential oil was studied against bacterial laboratory ATCC standards using the disk diffusion method. The results showed activity against Gram (+) bacteria and Escherichia coli. Little antibacterial activity was found against Pseudomonas aeroginosa.