Focal segmental glomerulosclerosis; collapsing variant
Peyman Mohammadi Torbati
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© 2012, Society of Diabetic Nephropathy Prevention. All rights reserved. Implication for health policy/practice/research/medical education: Collapsing focal segmental glomerulosclerosis presents a dramatic pattern of injury. Glomerular capillary lumina are occluded by an implosive wrinkling and collapse of the glomeular basement membranes (GBMs) that is more often global than segmental, without predilection for the perihilar segments. This GBM collapse is best delineated with the use of the PAS or the Jones methenamine silver stains.