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dc.contributor.authorMozhgan Hashemieh
dc.contributor.authorBahar Mansoori
dc.contributor.authorReza Tavakoli
dc.contributor.authorKoroush Sheibani
dc.date.accessioned2017-09-18T10:00:23Z
dc.date.available2017-09-18T10:00:23Z
dc.date.issued2012-06-01
dc.identifier.issn20082150
dc.identifier.urihttp://dsp.sbmu.ac.ir/xmlui/handle/123456789/61196
dc.description.abstractBackground: Proteus syndrome is a very rare condition with less than 100 confirmed cases reported worldwide. We report a case of Proteus syndrome in a two-year-old male who has hemophilia A comorbidity. Case Presentation: A two-year-old male patient was admitted with the chief complaint of severe bleeding in mouth cavity after trauma for two weeks. At admission he was found to have petechiae on buccal mucosa and fecal discoloration due to GI bleeding. We noted multiple abnormalities in his musculoskeletal system and skin. He had lymph edema in left leg, hemihypertrophy, macrodactyly in both foots and macrocephaly. With the history of severe bleeding and recurrent blood product transfusion, we suspected a hemorrhagic disorder. The reduced level of Factor VIII activity confirmed the diagnosis of hemophilia A. Considering patient's various musculoskeletal abnormalities according to the diagnostic criteria and after ruling out similar disorders the diagnosis of Proteus syndrome was established. Conclusion: Because of the variability of clinical features, Proteus syndrome can be confused with other disorders of multiple tissue overgrowth. Our case of Proteus syndrome, who had hemophilia A comorbidity outlines the challenges in diagnosis of such rare combination of diseases. © 2012 by Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences.
dc.sourceIranian Journal of Pediatrics
dc.subjectHemophilia A
dc.subjectMusculoskeletal
dc.subjectProteus syndrome
dc.titleA case of concurrent proteus syndrome and hemophilia A
dc.journal.volume22
dc.journal.issue2
dc.journal.pages255-259
dc.contributor.authorid55391988800
dc.contributor.authorid56590645200
dc.contributor.authorid55391091800
dc.contributor.authorid55140042400
dc.contributor.citation55391988800|60018934|Mozhgan Hashemieh
dc.contributor.citation56590645200|60018934|Bahar Mansoori
dc.contributor.citation55391091800|60018934|Reza Tavakoli
dc.contributor.citation55140042400|60018934|Koroush Sheibani
dc.contributor.affiliationid60018934
dc.contributor.affiliationid60018934
dc.contributor.affiliationid60018934
dc.contributor.affiliationid60018934


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