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dc.contributor.authorFakhrolmolouk Yassaee
dc.contributor.authorRoghieh Eskandari
dc.contributor.authorZohreh Amiri
dc.date.accessioned2017-09-18T09:58:05Z
dc.date.available2017-09-18T09:58:05Z
dc.date.issued2012-09-01
dc.identifier.issn20082177
dc.identifier.urihttp://dsp.sbmu.ac.ir/xmlui/handle/123456789/60889
dc.description.abstractBackground: Idiopathic thrombocytopenic purpura (ITP) is a disease that commonly affects women of reproductive age and is associated with maternal and fetal complications. Objective: The aim of the present study was to report the perinatal outcome in pregnant women with ITP. Materials and Methods: Twenty one pregnant women with ITP admitted in a teaching hospital in Tehran, from October 2008 to February 2010, were enrolled in this prospective historical cohort study; course and perinatal outcome of pregnancies were studied. Results: Seven (33.3%) cases had been diagnosed before pregnancy, while the other fourteen (66.7%) were diagnosed during pregnancy. During hospitalization, thirteen (62%) patients required treatment, eight (61.5%) of them with steroids, two (15.3%) received intravenous immunoglobulin (IVIG), and three (23%) were treated with steroids and IVIG. Three babies were delivered vaginally (14.3%), seventeen (81%) through cesarean section and one patient aborted her fetus. Nine mothers (42.9%) had platelet counts < 50000/ml at the time of delivery; but postpartum hemorrhage occurred in 4 (19%) women and one women received platelet transfusion during cesarean section. Six (28.6%) women developed gestational diabetes. Pregnancy was complicated by preeclampsia in one woman and by abruptio placenta in another. One pregnancy terminated in intrauterine fetal death. Seventeen infants (89.5%) had normal platelet counts, and two (10.5%) had moderate thrombocytopenia. No infant showed signs of hemorrhage, but 2 neonates (10.5%) were diagnosed with intrauterine growth restriction. Conclusion: Rate of gestational diabetes in pregnant women with ITP is higher than the general population. Rate of gestinational diabetes is 3-5% and postpartum hemorrhage is 5-7% in general. Postpartum hemorrhage is common in these women. Severe thrombocytopenia and bleeding in the newborns are uncommon.
dc.sourceIranian Journal of Reproductive Medicine
dc.subjectIdiopathic thrombocytopenic purpura
dc.subjectNeonatal outcome
dc.subjectPregnancy outcomes
dc.titlePregnancy outcomes in women with idiopathic thrombocytopenic purpura
dc.journal.volume10
dc.journal.issue5
dc.journal.pages489-492
dc.contributor.authorid57192658431
dc.contributor.authorid57188680273
dc.contributor.authorid36112604300
dc.contributor.citation57192658431|60018934|Fakhrolmolouk Yassaee
dc.contributor.citation57188680273|60018934|Roghieh Eskandari
dc.contributor.citation36112604300|60018934|Zohreh Amiri
dc.contributor.affiliationid60018934
dc.contributor.affiliationid60018934
dc.contributor.affiliationid60018934


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