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dc.contributor.authorA. Foroumadi
dc.contributor.authorS. A. Tabatabai
dc.contributor.authorG. Gitinezhad
dc.contributor.authorM. R. Zarrindast
dc.contributor.authorA. Shafiee
dc.date.accessioned2017-09-18T09:22:33Z
dc.date.available2017-09-18T09:22:33Z
dc.date.issued2000-01-01
dc.identifier.urihttp://dsp.sbmu.ac.ir/xmlui/handle/123456789/58766
dc.description.abstract5-Aryl-1,3,4-thiadiazole derivatives were synthesized and tested for anticonvulsant activity using the pentylenetetrazole-induced lethal convulsion test. The results showed that 2-amino derivatives have anticonvulsant activity (LD50 > 500 mg kg -1 ) and this effect was not mediated through benzodiazepine receptors. The fluoro electron-withdrawing substituent on the phenyl ring did not potentiate the activity of the compounds.
dc.sourcePharmacy and Pharmacology Communications
dc.titleSynthesis and anticonvulsant activity of 5-aryl-1,3,4-thiadiazole derivatives
dc.journal.volume6
dc.journal.issue1
dc.journal.pages31-33
dc.contributor.authorid7003549932
dc.contributor.authorid6602151112
dc.contributor.authorid6504599805
dc.contributor.authorid7103216110
dc.contributor.authorid7102727899
dc.contributor.citation7003549932|60017669|A. Foroumadi
dc.contributor.citation6602151112|60018934|S. A. Tabatabai
dc.contributor.citation6504599805|60027708|G. Gitinezhad
dc.contributor.citation7103216110|60027708|M. R. Zarrindast
dc.contributor.citation7102727899|60027708|A. Shafiee
dc.contributor.affiliationid60017669
dc.contributor.affiliationid60018934
dc.contributor.affiliationid60027708
dc.contributor.affiliationid60027708
dc.contributor.affiliationid60027708


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