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hOGG1 gene polymorphism and breast cancer risk: A systematic review and meta-analysis study
(2017-01-01)
© 2017 Wiley Periodicals, Inc. To address the effect of hGGO1 (rs1052133) gene polymorphism on the risk of breast cancer, a meta-analysis was performed. We pooled adjusted odds ratios (OR) as overall and three subgroups ...
Association study of the vesicular monoamine transporter 1 (VMAT1) gene with autism in an Iranian population
(2017-08-20)
Copyright © 2017 Elsevier B.V. All rights reserved. Autism Spectrum Disorders (ASD) (MIM 209850) are a group of neurodevelopmental disorders distinguished by destructed social interaction and communication abilities along ...
In silico dissection of miRNA targetome polymorphisms and their role in regulating miRNA-mediated gene expression in esophageal cancer
(2016-12-01)
© 2016, Springer Science+Business Media New York. Esophageal cancer is the eighth most common cancer worldwide. Also middle-aged obese adults with higher body mass index during childhood have a greater risk to develop ...
SNAP-25 gene variations and attention-deficit hyperactivity disorder in Iranian population
(2016-11-01)
© 2016 Informa UK Limited, trading as Taylor & Francis Group. Objectives: Attention deficit hyperactivity disorder (ADHD) is a common psychiatric condition of childhood characterized by persistent symptoms of hyperactivity, ...
SIPA1L2, MIR4697, GCH1 and VPS13C loci and risk of Parkinson's diseases in Iranian population: A case-control study
(2016-10-15)
© 2016 Elsevier B.V. Parkinson's disease (PD) is the second most common neurodegenerative disorder. Prevalence of PD increases steadily with age. A recent meta-analysis of genome-wide association studies has identified six ...
Genetic variants and expression study of FOXP3 gene in acute coronary syndrome in Iranian patients
(2016-04-01)
© 2016 John Wiley & Sons, Ltd. Acute coronary syndrome (ACS) is the most serious form of coronary artery disease. Inflammatory processes participate in different stages of this disorder. FOXP3 gene plays an important ...
Association of XPC gene polymorphisms with prostate cancer risk
(2016-01-01)
Background: Defective DNA repair capacity caused by inherited polymorphisms could be associated with cancer susceptibility. One of the major repair pathways is Nucleotide Excision Repair (NER). We investigated Xeroderma ...
Myxovirus resistance protein A (MxA) polymorphism is associated with IFNβ response in Iranian multiple sclerosis patients
(2017-06-01)
© 2017, Springer-Verlag Italia. Multiple sclerosis (MS) is a heterogeneous immune-related demyelinating disorder of central nervous system with several genetic and environmental factors contributing in its pathogenesis or ...
Association between polymorphisms in TP53 and MDM2 genes and susceptibility to prostate cancer
(2017-04-01)
© 2017, Spandidos Publications. All rights reserved. Tumor protein 53 (TP53), a tumor suppressor gene, is a vital cellular cancer suppressor in multicellular organisms. Murine double minute-2 (MDM2) is an oncoprotein that ...
Parental cigarette smoking, transforming growth factor-alpha gene variant and the risk of orofacial cleft in Iranian infants
(2016-04-01)
© 2016, Mashhad University of Medical Sciences. All rights reserved. Objective(s): We investigated the influence of genetic variation of the transforming growth-factor alpha (TGFA) locus on the relationship between smoking ...