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HIV and tuberculosis trends and survival of coinfection in a referral center in Tehran: A 12-year study
(2016-12-01)
© 2016 Objective/background The risk of mortality and morbidity among tuberculosis (TB) and human immunodeficiency virus (HIV) coinfected patients is significantly higher than that of patients infected with TB alone. The ...
Investigation of urine lipoarabinomannan in human immunodeficiency virus patients with or without coinfection with Tuberculosis in Iran
(2016-12-01)
© 2016 Objective/background Tuberculosis (TB) remains the leading cause of AIDS-related deaths among adults in countries with resource limitations. The emergence of the Xpert MTB/RIF rapid molecular assay and its subsequent ...
A randomized controlled trial of smoking cessation methods in patients newly-diagnosed with pulmonary tuberculosis
(2016-08-05)
© 2016 The Author(s). Background: Tuberculosis (TB) and tobacco use are two major alarming global health issues that tend to be co-prevalent in many developing countries and various surveys have provided evidence on their ...
Prevalence of HLA-B*5701 and its relationship with abacavir hypersensitivity reaction in Iranian HIV-infected patients
(2016-01-01)
© 2016 NRITLD, National Research Institute of Tuberculosis and Lung Disease, Iran. Background: Hypersensitivity reaction (HSR) is a major adverse effect of abacavir (ABC), which occurs in 5-8% of Caucasians. The relationship ...
Treatment of multiple drug-resistant tuberculosis (MDR-TB) in Iran
(2005-11-01)
Setting: Masih Daneshvari Hospital, Tehran, Iran, 2000-2002. Objective: To evaluate the effectiveness of multiple drug-resistant tuberculosis (MDR-TB) treatment for the first time in Iran. Design: All cases of MDR-TB with ...
Outcome of treatment of MDR-TB patients with standardised regimens, Iran, 2002-2006
(2008-07-01)
BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) imposes a formidable burden on national health systems. There is still no consensus on the subject, with controversies regarding treatment protocols, treatment outcomes ...
Performance of QuantiFERON-TB Gold test compared to tuberculin skin test in detecting latent tuberculosis infection in HIV- positive individuals in Iran
(2010-01-01)
Background: There is limited data about the performance of QuantiFERON-TB Gold (QFT-G) test in detecting latent tuberculosis infection (LTBI) in our region. We intended to determine the performance of QFT-G compared to ...
First-line anti-tuberculosis drug resistance patterns and trends at the national TB referral center in Iran-eight years of surveillance
(2009-09-01)
Objective: Resistance to anti-tuberculosis (anti-TB) drugs is becoming a major and alarming threat in most regions worldwide. Methods: This was a descriptive cross-sectional study at a tertiary hospital in Iran, using ...
Primary immune deficiencies presenting in adults: Seven years of experience from Iran
(2005-07-01)
Primary immunodeficiencies (PIDs) are not solely diseases of childhood. We describe the clinical presentation and outcome for 55 adult patients with previously unrecognized PIDs. This series provides unique data regarding ...
Representative drug susceptibility patterns for guiding design of re-treatment regimens for multidrug-resistant tuberculosis in Iran
(2008-01-01)
Background and objective: The prevalence of multidrug-resistant tuberculosis (MDR-TB) has increased substantially in the past 20 years, however, there are no data specific to Iran. This study investigated patients suspected ...