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Extensively drug-resistant tuberculosis: A review article
(2012-01-01)
Extensively Drug-Resistant Tuberculosis (XDR-TB) is a new challenge for Tuberculosis control programs. Lack of effective drugs and high rate of failure in treatment and mortality is a major threat for public health. Treatment ...
First-line anti-tuberculosis drug resistance patterns and trends at the national TB referral center in Iran-eight years of surveillance
(2009-09-01)
Objective: Resistance to anti-tuberculosis (anti-TB) drugs is becoming a major and alarming threat in most regions worldwide. Methods: This was a descriptive cross-sectional study at a tertiary hospital in Iran, using ...
Comparison of polymerase chain reaction single-strand conformation polymorphism with DNA sequencing to detect drug resistance of mycobacterium tuberculosis isolates
(2011-12-01)
Objectives: Advancements in molecular technology increased our understanding of genetic mechanism of drug resistance. Nowadays, the chance of rapid detection of resistant Mycobacterium tuberculosis (M. tuberculosis) strains ...
Smoking effects on clinical manifestations and drug resistance patterns in pulmonary TB patients
(2010-12-01)
Background: Considering the rising trend of tuberculosis (TB) and cigarette smoking, an evaluation of the clinical manifestations and drug resistance patterns in TB patients with regard to smoking status seemed beneficial. ...