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Bovis Bacillus Calmette-Guerin (BCG) infection induces exosomal miRNA release by human macrophages
(2017-05-12)
© 2017 The Author(s). Background: Tuberculosis (TB) remains a significant global health concern and its diagnosis is challenging due to the limitations in the specificity and sensitivity of the current diagnostic tests. ...
Comparison of pulmonary TB patients with and without diabetes mellitus type II
(2010-08-09)
Background: There are several studies on the effect of diabetes mellitus (DM) on clinical symptoms and radiological findings of multi-drug resistant tuberculosis (MDR-TB) and bacteriological findings in pulmonary tuberculosis ...
Chronic granulomatous disease with unusual clinical manifestation, outcome, and pattern of inheritance in an Iranian family
(2006-05-01)
CGD is a rare phagocytic disorder manifesting as recurrent, severe bacterial and fungal infections. We describe an Iranian family with eight children, of whom six, five males and one female were diagnosed with CGD resulting ...
The recent-transmission of Mycobacterium tuberculosis Strains among Iranian and Afghan relapse cases: A DNA-fingerprinting using RFLP and spoligotyping
(2008-08-06)
Background: Relapse of tuberculosis (TB) may develop as the result of reactivation of the endogenous primary infection, or as a result of a exogenous reinfection. This survey evaluated the rate of reactivation versus ...
Inherited disorders of the IL-12-IFN-γ axis in patients with disseminated BCG infection
(2005-12-01)
Disseminated BCG infection is a rare complication of vaccination that occurs in patients with impaired immunity. In recent years, a series of inherited disorders of the IL-12-IFN-γ axis have been described that predispose ...
Lymphocytic bronchiolitis as presenting disorder in an undiagnosed adult patient with chronic granulomatous disease
(2007-12-01)
Chronic Granulomatous Disease (CGD) is a rare primary immunodeficiency disease. Although the most affected patients are diagnosed in childhood, there are several reports of the disease presenting in adult patients. Here ...
Utility of gastric lavage for diagnosis of tuberculosis in patients who are unable to expectorate sputum
(2011-10-01)
Background: There are number of patients who are unable to expectorate sputum specimens. In this study, we used gastric lavage (GL) test for diagnosis of tuberculosis (TB) in patients who were unable to produce sputum. ...
Recurrent drug-induced hepatitis in tuberculosis-comparison of two drug regimens
(2017-01-01)
© 2014 Lippincott Williams & Wilkins. Drug-induced hepatitis (DIH) is one of the major complications among the treatment of patients with tuberculosis (TB); it might even be fatal. This study tries to address the recurrence ...
Nontuberculous mycobacteria among patients who are suspected for multidrug-resistant tuberculosis - Need for earlier identification of nontuberculosis mycobacteria
(2009-03-01)
BACKGROUND: In this study, we intended to find the prevalence of nontuberculosis mycobacteria (NTM) among patients who are referred as suspected multidrug-resistant tuberculosis (MDR-TB) cases to the only referral center ...