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Identification of sequence variation in the apolipoprotein A2 gene and their relationship with serum high-density lipoprotein cholesterol levels
(2016-04-01)
© 2016, Pasteur Institute of Iran. All rights reserved. Background: Apolipoprotein A2 (APOA2) is the second major apolipoprotein of the high-density lipoprotein cholesterol (HDL-C). The study aim was to identify APOA2 gene ...
Genetic polymorphisms in the APOA1 gene and their relationship with serum HDL cholesterol levels
(2013-12-01)
Low high density lipoprotein cholesterol (HDL-C) is a known risk factor of coronary artery disease. Apolipoprotein A1 (APOA1) is the most abundant component of HDL-C. This study aimed at identifying sequence variations ...
A comparison of lecithin cholesterol acyltransferase gene variation among individuals with high and low HDL levels in Tehran Lipid And Glucose Study (TLGS)
(2015-01-01)
© 2015, Endocrine Research Center. All rights reserved. Introduction: Disturbances in blood lipids levels are considered an important risk factor for cardiovascular diseases. Low serum level of HDL-C is one of these ...
Association of lecithin cholesterol acyltransferase rs5923 polymorphism in Iranian individuals with extremely low high- density lipoprotein cholesterol: Tehran lipid and glucose study
(2015-07-01)
© 2015, Pasteur Institute of Iran. All rights reserved. Background: The serum concentration of high-density lipoprotein cholesterol (HDL-C) is one of the important heritable risk factors for cardiovascular disease and is ...
No association of the SUMO4 polymorphism M55V variant in type 2 diabetes in Iranian subjects
(2010-11-01)
Introduction: Diabetes mellitus incidence has an increasing rate and it's genetic aspect is an important approach as a risk factor and predictive value in this disorder. In some population, SUMO4, a regulator of NF-κB, ...
Association between TPO gene polymorphisms and Anti-TPO level in Tehranian population: TLGS
(2012-04-25)
Introduction: Thyroid peroxidase (TPO) gene variations are one cause of thyroid autoimmune diseases. The aim of this study was to examine the association between the T1936C, T2229C and A2257C polymorphisms of the TPO gene ...
Single nucleotide polymorphism of rs1800247 in promoter region of osteocalcin gene in patients with medullary thyroid carcinoma
(2014-01-01)
Background: Medullary thyroid carcinoma is a malignant tumor originated from parafollicular cells. Osteocalcin (OC) is the most non-collagenous protein in bone and its gene is located on chromosome 1 (1q25-q31). Important ...
The age effect on the association between the scavenger receptor class B type I (SR-BI) polymorphism and HDL-C level: Tehran Lipid and Glucose Study
(2014-01-01)
Introduction: The scavenger receptor class B type I (SR-BI) is a key component in the reverse cholesterol transportation. The aim of this study was to assess the association between exon1 (G → A) polymorphism of SR-BI gene ...
Association of vitamin D levels and receptor gene polymorphisms with medullary thyroid cancer
(2016-07-01)
© 2016, Tehran University of Medical Sciences. All rights reserved. Background: Thyroid cancer is the most common endocrine malignancy. Accounting for approximately 1-2% of all cancers. Thyroid cancers have been divided ...