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Plasma calcitonin levels and miRNA323 expression in medullary thyroid carcinoma patients with or without RET mutation
(2017-08-01)
Background: Medullary thyroid cancer (MTC) is an endocrine tumor featuring parafollicular or C-cell differentiation, with calcitonin as a specific biomarker in MTC diagnosis. Germline mutations in the RET proto-oncogene ...
Germline mutations of RET proto-oncogene exon 2 in Iranian population with medullary thyroid carcinoma
(2016-03-01)
© 2016, Semnan University of Medical Sciences. All rights reserved. Introduction: Medullary thyroid carcinoma (MTC) accounts for 5-10% of all thyroid cancers andit is inherited in autosomal dominant pattern. Association ...
Diversity of mutations in the RET proto-oncogene and its oncogenic mechanism in medullary thyroid cancer
(2016-07-03)
© 2016 Informa UK Limited, trading as Taylor & Francis Group. Abstract: Thyroid cancer is the most common endocrine malignancy and accounts for nearly 1% of all of human cancer. Thyroid cancer has four main histological ...
Effect of pomegranate seed oil on serum TNF-α level in dyslipidemic patients
(2012-05-01)
Pomegranate punicic acid and pomegranate fruit extracts have the potential effects in inhibiting tumour necrosis factor-α (TNF-α) and inflammatory diseases. The aim of this study was to evaluate the effect of pomegranate ...
Apolipoprotein e polymorphisms status in Iranian patients with multiple sclerosis
(2012-09-15)
Background: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central nervous system. Evidences linking apolipoprotein E (APOE) to myelin repair, neuronal plasticity, and cerebral inflammatory ...
RET proto oncogene mutation detection and medullary thyroid carcinoma prevention
(2015-01-01)
the most aggressive forms of thyroid malignancy, accounting for up to 10% of all types of this disease. The mode of inheritance of MTC is autosomal dominantly and gain of function mutations in the RET proto-oncogene are ...
Plasma levels of osteocalcin and retinol binding protein-4 in patients with medullary thyroid carcinoma
(2014-01-01)
Background: Thyroid carcinoma is the most frequent malignant tumor of the endocrine system in human body and accounts for nearly 1% of all cancers. Medullary thyroid carcinoma is the third frequent of thyroid cancer and ...
Skewed mutational spectrum of RET proto-oncogene Exon10 in Iranian patients with medullary thyroid carcinoma
(2015-07-29)
© 2015, International Society of Oncology and BioMarkers (ISOBM). Thyroid cancer is the most common endocrine malignant tumor. Medullary thyroid carcinoma (MTC) is an aggressive tumor arising from calcitonin-producing ...
Germline mutation of RET proto-oncogene’s exons 17 and 18 in Iranian medullary thyroid carcinoma patients
(2017-03-01)
© 2017, Tehran University of Medical Sciences. All rights reserved. Background: Thyroid carcinoma is the most common endocrine malignancy. Medullary thyroid carcinoma (MTC) approximately accounts for 5-10% of all thyroid ...
Point mutations in ret proto-oncogene exon 10 in patients with medullary thyroid carcinoma
(2015-01-01)
© 2015, Kerman University of Medical Sciences. All rights reserved. Background & Aims: Thyroid cancer is the most common endocrine malignancy. Medullary thyroid carcinoma (MTC) is an aggressive malignant tumor arising ...